tech
December 31, 2025
‘They didn’t de-extinct anything’: can Colossal’s genetically engineered animals ever be the real thing?
The bioscience startup has attracted billions in investment – and a flurry of criticism, but founder tells the Guardian plans to bring back the woolly mammoth will not be derailed

TL;DR
- Colossal Biosciences has raised billions and is pursuing de-extinction projects like reviving the woolly mammoth.
- The company claims to have resurrected the dire wolf and created "woolly mice."
- Public announcements have generated significant excitement and investment, including from notable figures.
- Scientists criticize Colossal's claims, stating they are creating genetically engineered animals, not true de-extinctions.
- Critics argue overhyped claims undermine public trust in science.
- Colossal plans to unveil a genetically modified Asian elephant adapted to cold climates as its interpretation of the woolly mammoth.
- Scientists critical of Colossal have reportedly been targeted by smear campaigns.
- Colossal's founder argues their work can revitalize conservation efforts and inspire interest in biodiversity.
- Experts acknowledge gene editing's potential for living species but state de-extinction cannot replace traditional conservation methods.
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