tech

December 31, 2025

‘They didn’t de-extinct anything’: can Colossal’s genetically engineered animals ever be the real thing?

The bioscience startup has attracted billions in investment – and a flurry of criticism, but founder tells the Guardian plans to bring back the woolly mammoth will not be derailed

‘They didn’t de-extinct anything’: can Colossal’s genetically engineered animals ever be the real thing?

TL;DR

  • Colossal Biosciences has raised billions and is pursuing de-extinction projects like reviving the woolly mammoth.
  • The company claims to have resurrected the dire wolf and created "woolly mice."
  • Public announcements have generated significant excitement and investment, including from notable figures.
  • Scientists criticize Colossal's claims, stating they are creating genetically engineered animals, not true de-extinctions.
  • Critics argue overhyped claims undermine public trust in science.
  • Colossal plans to unveil a genetically modified Asian elephant adapted to cold climates as its interpretation of the woolly mammoth.
  • Scientists critical of Colossal have reportedly been targeted by smear campaigns.
  • Colossal's founder argues their work can revitalize conservation efforts and inspire interest in biodiversity.
  • Experts acknowledge gene editing's potential for living species but state de-extinction cannot replace traditional conservation methods.

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