health
March 10, 2026
FDA declines to approve leucovorin for autism
The Trump administration appears to be walking back its statements from last year that the prescription drug leucovorin can be used to treat certain patients with autism.
TL;DR
- The Trump administration had previously suggested leucovorin could treat autism.
- The FDA updated leucovorin's label to include cerebral folate deficiency but not autism.
- Agency officials cited insufficient evidence for leucovorin's use in treating autism.
- A study linking supplemental folate to improved autism symptoms was retracted.
- Cerebral folate deficiency affects folate levels in the brain, impacting speech, thinking, and movement.
Continue reading the original article