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February 9, 2026

The Twins That Are Neither Identical nor Fraternal

They shared a placenta, but on the ultrasound, one looked like a boy, and the other a girl.

The Twins That Are Neither Identical nor Fraternal

TL;DR

  • Sesquizygotic twins are a rare type of twin that is neither identical nor fraternal.
  • They likely result from an egg fertilized by two sperm (one X, one Y) and subsequent complex cell sorting.
  • The twins are chimeras, possessing a mix of XX and XY cells in varying proportions.
  • This is the second documented case of sesquizygotic twins, highlighting their extreme rarity.
  • One twin experienced an arm amputation due to a blood clot and surgery for an ovarian abnormality related to chimerism.

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