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Revolution Medicines says its potential breakthrough pancreatic cancer drug succeeds in late-stage trial

Revolution Medicines' drug for pancreatic cancer succeeded in a highly anticipated Phase 3 trial, the company said.

Revolution Medicines says its potential breakthrough pancreatic cancer drug succeeds in late-stage trial

TL;DR

  • Daraxonrasib, Revolution Medicines' drug, met all primary and secondary endpoints in a Phase 3 trial for pancreatic cancer.
  • Patients taking daraxonrasib lived 13.2 months on average, compared to 6.7 months for those on chemotherapy, nearly doubling survival time.
  • The drug reduced the risk of death by 60% and is seen as a significant advancement for pancreatic cancer treatment.
  • Daraxonrasib targets RAS mutations, which are present in about 90% of pancreatic cancer cases.
  • The company plans to seek FDA approval using a National Priority Voucher for a faster review.
  • Former Sen. Ben Sasse shared his positive experience with the drug, noting tumor shrinkage but also manageable side effects like a facial rash.
  • The drug showed a manageable safety profile with no new concerns observed in the study.
  • Revolution Medicines' stock surged over 30% following the trial results.