health

A mom's Stage IV cancer had no symptoms. An innovative surgery saved her life.

When Amy Piccoli's son brought home a stomach bug in May 2024, she thought she knew what she was in for. The Los Angeles mom of three was used to seasonal illnesses and 24-hour viruses.

A mom's Stage IV cancer had no symptoms. An innovative surgery saved her life.

TL;DR

  • Amy Piccoli was diagnosed with Stage IV colon cancer in May 2024, with no prior symptoms or family history.
  • The diagnosis was a shock, as she was diligent about her health and experienced no typical warning signs.
  • Treatment initially involved chemotherapy and immunotherapy, leading to tumor shrinkage but not complete removal of liver tumors.
  • Piccoli pursued a novel liver transplant procedure, which can dramatically increase five-year survival rates for eligible patients.
  • She received a transplant from a living donor in December 2025 at Northwestern Medicine and is now undergoing follow-up scans.
  • The procedure is described as transforming 'hospice into hope' for patients with limited options.