Wall Street's top stock picks for 2026: Mizuho’s under-the-radar name that could more than triple in value

Based on its 12-month price target, Mizuho sees shares of Vaxcyte soaring almost 300% from current levels.

Wall Street's top stock picks for 2026: Mizuho’s under-the-radar name that could more than triple in value

TL;DR

  • Mizuho sees over 250% upside potential in Vaxcyte (PCVX).
  • Vaxcyte's pneumococcal vaccine platform is seen as de-risked following Phase 2 readouts.
  • The adult-catered vaccine (VAX-31) shows potential to be best-in-class with broad serotype coverage.
  • While infant vaccine data (VAX-24) was imperfect, steps have been taken to mitigate risks and improve future readouts.
  • The $8 billion pneumococcal disease vaccine market is growing, with Vaxcyte's competitors lagging in development.

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